COVID-19 EMERGENCY SUPPORT

IMPACT ON AKI AND CRRT

  • Even in COVID patients who have normal kidney function at hospital admission, the risk for acute kidney injury (AKI) is very high.28
    • There is some evidence that COVID-19 interferes with kidney function itself.28
    • The rate is increased greatly in the setting of severe respiratory failure and acute respiratory distress syndrome (ARDS).31
  • The Percentage of Intubated ICU patients with AKI that necessitates Renal Replacement Therapy has been reported between 15-40%.28,29,31
  • The consequences of AKI in mechanically ventilated patients are important, as the independent mortality of AKI in the intensive care unit (ICU) is 30–50%, and patients with combined respiratory failure and AKI have a mortality of 60–80%.30

A progress of 5,449 patients admitted to one of 13 hospitals in the New York City area between March 1 and April 5, 2020 was assessed by a team from the Northwell COVID-19 Research Consortium. There were no transplant or dialysis patients in the study cohort, yet even without compromised kidney function:29

ALL PATIENTS
PATIENTS ON MECHANICAL VENTILATION